Article
Genetic polymorphisms of VKORC1, CYP2C9, CYP4F2 in Bai, Tibetan Chinese.
Die Pharmazie - 1 Jan 2012
Zeng W T, Zheng Q S, Huang M, Cen H J, Lai Y, Chen W Y, Zhao L Z, Leng X Y
Abstract excerpt
BACKGROUND: VKORC1, CYP2C9 and CYP4F2 are three critical genes associated with inter-individual variation of warfarin dose. Many dosing algorithms containing these gene polymorphisms and demographic characteristics have been set up for better use of warfarin. However, with distinct gene mutation frequencies among different ethnics, dosing algorithms differ greatly. For Chinese, related research just concentrate...
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