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Article

The Association of ADRB1 and CYP2D6 Polymorphisms With Antihypertensive Effects and Analysis of Their Contribution to Hypertension Risk.

The American journal of the medical sciences - 1 Mar 2018

Chen Liping, Xiao Ting, Chen Liling, Xie Shanshan, Deng Maoqing, Wu Dingchang

Abstract excerpt

BACKGROUND: Genetic factors have a vital influence on the pathogenesis of hypertension. In this retrospective study, we aimed to evaluate the association of ADRB1 and CYP2D6 polymorphisms with antihypertensive effects and perform an analysis of their contribution to hypertension risk. METHODS: A total of 261 healthy individuals and 261 essential hypertension patients treated with metoprolol for 12 weeks were...

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Source

Identifiers

PMID: 29549925
DOI: 10.1016/j.amjms.2017.11.002

Genes

ADRB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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