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Article

Associations between ADRB1 and CYP2D6 gene polymorphisms and the response to β-blocker therapy in hypertension.

The Journal of international medical research - 1 Jun 2015

Wu Dingchang, Li Ganyang, Deng Maoqing, Song Wei, Huang Xiaohua, Guo Xiaoru, Wu Zhengzheng, Wu Shiyang, Xu Jiasen

Abstract excerpt

OBJECTIVE: To investigate the associations between β1-adrenergic receptor (ADRB1) and cytochrome P450 2D6 (CYP2D6) gene polymorphisms and β-blocker treatment outcomes in patients with hypertension. METHODS: Chinese patients with essential hypertension were treated with the β-blocker metoprolol and followed up for 12 weeks. xTAG® liquid-chip technology was used for CYP2D6 100 C > T and ADRB1 1165G > C genotyping....

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Share to Adrenergic beta-Antagonists
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25823457
DOI: 10.1177/0300060514563151

Genes

ADRB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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