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Article

TRABD modulates mitochondrial homeostasis and tissue integrity

1 Jun 2024

Abstract excerpt

High TRABD expression is associated with tau pathology in patients with Alzheimer's disease; however, the function of TRABD is unknown. Human TRABD encodes a mitochondrial outer-membrane protein. The loss of TRABD resulted in mitochondrial fragmentation, and TRABD overexpression led to mitochondrial clustering and fusion. The C-terminal tail of the TRABD anchored to the mitochondrial outer membrane and the TraB...

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PMID: 38843396
DOI: 10.1016/j.celrep.2024.114304

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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