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Article

ATAD3A: A Key Regulator of Mitochondria-Associated Diseases.

International journal of molecular sciences - 7 Aug 2023

Chen Liting, Li Yuchang, Zambidis Alexander, Papadopoulos Vassilios

Abstract excerpt

Mitochondrial membrane protein ATAD3A is a member of the AAA-domain-containing ATPases superfamily. It is important for the maintenance of mitochondrial DNA, structure, and function. In recent years, an increasing number of ATAD3A mutations have been identified in patients with neurological symptoms. Many of these mutations disrupt mitochondrial structure, function, and dynamics and are lethal to patients at a...

Topics

Humans
ATPases Associated with Diverse Cellular Activities
Mitochondrial Proteins
Mitochondria
Membrane Proteins
Mitochondrial Diseases
Mutation
Animals
DNA, Mitochondrial

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37569886
DOI: 10.3390/ijms241512511
PMCID: PMC10419812

Genes

ATAD3A

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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