Article
Clonal hematopoiesis of indeterminate potential is rare in pediatric patients undergoing autologous stem cell transplantation.
Pediatric hematology and oncology - 1 Oct 2024
Kartal-Kaess Mutlu, Karow Axel, Bacher Ulrike, Pabst Thomas, Joncourt Raphael, Zweier Christiane, Kuehni Claudia E, Porret Naomi Azur, Roessler Jochen
Abstract excerpt
Clonal hematopoiesis of indeterminate potential (CHIP) describes recurrent somatic gene mutations in the blood of healthy individuals, associated with higher risk for hematological malignancies and higher all-cause mortality by cardiovascular disease. CHIP increases with age and is more common in adult patients after chemotherapy or radiation for cancer. Furthermore, in some adult patients undergoing autologous...
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