Repair of platinum-DNA lesions in E. coli by a pathway which does not recognize DNA damage caused by MNNG or UV light.

doi:10.1016/0167-8817(85)90037-9

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Article

Repair of platinum-DNA lesions in E. coli by a pathway which does not recognize DNA damage caused by MNNG or UV light.

Mutation research - 1 Jan 2000

Germanier M, Defais M, Johnson N P, Villani G

Abstract excerpt

The adaptive response is an inducible DNA-repair system which diminishes the mutagenic and toxic effects of alkylating agents. A mutant of E. coli constitutive for adaptative repair, BS21, has been isolated. A spontaneous revertant of this strain, BS23, lacks the adaptive response. When compared...

Topics

Cisplatin
DNA Repair
DNA, Bacterial
Escherichia coli
Methylnitronitrosoguanidine
Mutation
Ultraviolet Rays

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