Article
[The adaptive response to mitomycin C exposure in the hyper-radioresistant mutant Escherichia coli Gamr444].
Tsitologiia - 1 Jan 1991
Zhestianikov V D, Savel'eva G E, Kalinin V L
Abstract excerpt
Adaptive response to mitomycin C (MC) (lethal effect and recovery of molecular mass of DNA) in hyper-radioresistant mutant Escherichia coli Gamr444 have been investigated. This mutant is more resistant to MC than parent strain E. coli K12 AB1157. Adaptation of Gamr444 mutant to MC in nonlethal concentrations increases its resistance to MC in lethal concentrations with dose modification factor (DMF) 2.4 at the...
Topics
- Adaptation, Physiological
- Alkylating Agents
- DNA Damage
- DNA Repair
- DNA, Bacterial
- Escherichia coli
- Gamma Rays
- Mitomycin
- Mitomycins
- Molecular Weight
- Mutation
- Radiation Tolerance
