Article
The level of GC-->AT transitions induced by MMS is not affected by the adaptive response in Escherichia coli K12.
Mutation research - 1 Jun 1993
Sledziewska-Gójska E
Abstract excerpt
I have examined the effect of the adaptive response on the frequency of MMS-induced umuC-dependent AT-->TA transversions and umuC-independent, GC-->AT transitions. It was found that the induction of the adaptive response causes a moderate decrease (50-60%) in the frequency of AT-->TA transversions and surprisingly has no effect on the level of GC-->AT transitions. In contrast, a dramatic decrease in MNNG-induced...
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