The level of GC-->AT transitions induced by MMS is not affected by the adaptive response in Escherichia coli K12.

doi:10.1016/0921-8777(93)90052-i

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Article

The level of GC-->AT transitions induced by MMS is not affected by the adaptive response in Escherichia coli K12.

Mutation research - 1 Jun 1993

Sledziewska-Gójska E

Abstract excerpt

I have examined the effect of the adaptive response on the frequency of MMS-induced umuC-dependent AT-->TA transversions and umuC-independent, GC-->AT transitions. It was found that the induction of the adaptive response causes a moderate decrease (50-60%) in the frequency of AT-->TA transversion...

Topics

DNA Repair
Deoxyribonuclease I
Escherichia coli
Methyl Methanesulfonate
Methylnitronitrosoguanidine
Methyltransferases
Mutagenesis
Mutagens
Mutation
O(6)-Methylguanine-DNA Methyltransferase
Suppression, Genetic

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