Adaptive resistance of Saccharomyces cerevisiae to chronic treatment with mutagens being due to a dominant mutation.

doi:10.1016/0027-5107(90)90070-k

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Article

Adaptive resistance of Saccharomyces cerevisiae to chronic treatment with mutagens being due to a dominant mutation.

Mutation research - 1 Feb 1990

Fahrig R, Kaspers I

Abstract excerpt

The exposure of mammalian cells or tumors for weeks or months to low non-lethal doses of cytostatic drugs may induce multi-drug resistance, which can be enhanced by a variety of DNA-damaging agents. In yeast multi-drug resistance to a variety of drugs has been observed. DNA-damaging agents have n...

Topics

4-Nitroquinoline-1-oxide
Adaptation, Physiological
Chi-Square Distribution
Crosses, Genetic
Drug Resistance, Microbial
Genes, Dominant
Genes, Fungal
Mutagens
Mutation
Recombination, Genetic
Saccharomyces cerevisiae
Spores, Fungal
Triethylenemelamine

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