Article
[Use of Escherichia coli recF mutant strains for analyzing the genotoxicity of complex platinum compounds].
Genetika - 1 Jul 1997
Ptitsyn L R, Riazanova L A, Ivanov V B
Abstract excerpt
The bioluminescence method of assessing SOS response in Escherichia coli cells was applied to test the genotoxicity of five complex platinum compounds: cis-diamminedichloroplatinum, cycloplatam, trans-diamminedichloroplatinum, and two trans-binuclear complexes. Strains AB1157 (pPLS-1) and JC9239 (pPLS-1), a variant of AB1157 carrying the recF143 mutation, were used in the test procedure. SOS response in JC9239...
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