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Macrocyclic lactone resistance in Dirofilaria immitis: risks for prevention of heartworm disease

27 Oct 2021

Abstract excerpt

Heartworm disease, caused by Dirofilaria immitis, can be lethal in dogs and cats. It is transmitted by mosquitoes, and occurs in many parts of the world. Prevention relies on macrocyclic lactones. Macrocyclic lactones used are ivermectin, selamectin, abamectin, eprinomectin, milbemycin oxime and moxidectin, administered at 30-day intervals during the transmission season. Some moxidectin formulations are...

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PMID: 34717929
DOI: 10.1016/j.ijpara.2021.08.006

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