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Article

Association of Polymorphisms in PD-1 and LAG-3 Genes with Acute Myeloid Leukemia.

Medicina (Kaunas, Lithuania) - 26 Apr 2024

Mansour Lamjed, Alqahtani Mashael, Aljuaimlani Ali, Al-Tamimi Jameel, Al-Harbi Nouf, Alomar Suliman

Abstract excerpt

Background and objectives: Acute myeloid leukemia (AML) is a hematological malignancy characterized by uncontrolled proliferation of immature myeloid cells. Immune checkpoint molecules such as programmed cell death protein 1 (PD-1) and lymphocyte activation gene-3 (LAG-3) are essential for controlling anti-tumor immune responses. This study aims to explore the correlation between specific genetic variations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38792904
DOI: 10.3390/medicina60050721
PMCID: PMC11123055

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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