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Article

Evaluation of the possible association of PDCD-1 and LAG3 gene polymorphisms with hepatocellular carcinoma risk.

BMC medical genomics - 2 May 2023

Wei Jiankai, Liao Zhangxiu, Tao Ying, Liu Shuaiting

Abstract excerpt

PURPOSE: Programmed death-1 (PDCD-1) and lymphocyte activating 3 (LAG3), two important immunosuppressive molecules, play crucial roles in immune escape of tumor cells. This study evaluated the effects of PDCD-1 (rs10204525 and rs36084323), and LAG3 (rs870849 and rs1882545) gene polymorphisms on hepatocellular carcinoma (HCC) risk. METHODS: 341 patients with HCC and 350 cancer-free controls in the South Chinese...

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Share to alpha-Fetoproteins
Share to Carcinoma, Hepatocellular
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Share to Polymorphism, Single Nucleotide
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Source

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Identifiers

PMID: 37131179
DOI: 10.1186/s12920-023-01526-7
PMCID: PMC10155321

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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