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The correlation between Flt3-ITD mutation in dendritic cells with TIM-3 expression in acute myeloid leukemia

1 Oct 2021

Abstract excerpt

In general, acute myeloid leukemia (AML) is an aggressive and heterogeneous disease that is characterized by rapid cellular proliferation and high mortality. One of the mutations related to AML is the Flt3-ITD mutation, which is found in approximately 25% of patients. In this mini-review, we investigate the function of dendritic cells and T cells based on Flt3-ITD mutation and immune evasion as a result of this...

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PMID: 35402842
DOI: 10.1097/bs9.0000000000000092

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