Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TIM3 and CTLA4 immune checkpoint polymorphisms are associated with acute myeloid leukemia in Saudi Arabia.

Hematology (Amsterdam, Netherlands) - 1 Dec 2024

Alqahtani Mashael, Aljuaimlani Ali, Al-Tamimi Jameel, Alomar Suliman, Mansour Lamjed

Abstract excerpt

BACKGROUND: Immune checkpoints are receptors on the surface of T cells that function crucially in suppressing the immune response, and they are implicated in autoimmunity and cancer diseases. AIM: The present study aimed to investigate the relationship between functional single nucleotide polymorphisms (SNPs) of two immune checkpoint molecules, CTLA-4 and TIM-3, and acute myeloid leukemia (AML) in a Saudi...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CTLA-4 Antigen
Share to Hepatitis A Virus Cellular Receptor 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia, Myeloid, Acute

Share to Polymorphism, Single Nucleotide

Share to Saudi Arabia

Source

Identifiers

PMID: 38536023
DOI: 10.1080/16078454.2024.2329024

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TIM3 and CTLA4 immune checkpoint polymorphisms are associated with acute myeloid leukemia in Saudi Arabia.PMID 38536023Read ↗

Immune checkpoint-related gene polymorphisms are associated with acute myeloid leukemia.Semantic proximity Read ↗

Association of Polymorphisms in PD-1 and LAG-3 Genes with Acute Myeloid Leukemia.Semantic proximity Read ↗

Expression of immune check point gene TIM‑3 in patients newly diagnosed with acute myeloid leukemia: Significance and impact on outcomeSemantic proximity Read ↗

Tim-3 is highly expressed in T cells in acute myeloid leukemia and associated with clinicopathological prognostic stratification.Semantic proximity Read ↗

The immune checkpoints Cytotoxic T lymphocyte antigen-4 and Lymphocyte activation gene-3 expression is up-regulated in acute myeloid leukemia.Semantic proximity Read ↗

Genetic polymorphisms of tumor necrosis factor receptor-associated factor 3 and their association with acute lymphoblastic leukemia.Semantic proximity Read ↗

TIM-3 Expression Level on AML Blasts Correlates With Presence of Core Binding Factor Translocations Rather Than Clinical OutcomesSemantic proximity Read ↗

The Variations' in Genes Encoding TIM-3 and Its Ligand, Galectin-9, Influence on ccRCC Risk and Prognosis.Semantic proximity Read ↗

Unravelling the potential of TIM-3 gene polymorphism in allogeneic hematopoietic stem cell transplantation - a preliminary study.Semantic proximity Read ↗

The correlation between Flt3-ITD mutation in dendritic cells with TIM-3 expression in acute myeloid leukemiaSemantic proximity Read ↗

TIM-3 polymorphism is involved in the progression of esophageal squamous cell carcinoma by regulating gene expression.Semantic proximity Read ↗

Genetic variants and expression of the TIM-3 gene are associated with clinical prognosis in patients with epithelial ovarian cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.