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Article

Immune checkpoint-related gene polymorphisms are associated with acute myeloid leukemia.

Cancer medicine - 1 Sept 2023

Wu Yuyan, Li Mingying, Meng Guangqiang, Ma Yuechan, Ye Jingjing, Sun Tao, Ji Chunyan

Abstract excerpt

BACKGROUND: Chemotherapy is still the standard regimen for treating acute myeloid leukemia (AML) and its disappointing efficacy requires the urgent need for new therapeutic targets. It is well known that immune response plays an increasingly significant role in the pathogenesis of AML. METHODS: We detected nine single nucleotide polymorphisms (SNPs) in immune checkpoint-related genes, including PD1, LAG3, TIM3,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 37602517
DOI: 10.1002/cam4.6468
PMCID: PMC10557852

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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