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The Role of Long Noncoding RNAs in Human Papillomavirus-associated Pathogenesis

15 Apr 2020

Abstract excerpt

Infections with high-risk human papillomaviruses cause ~5% of all human cancers. E6 and E7 are the only viral genes that are consistently expressed in cancers, and they are necessary for tumor initiation, progression, and maintenance. E6 and E7 encode small proteins that lack intrinsic enzymatic activities and they function by binding to cellular regulatory molecules, thereby subverting normal cellular...

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PMID: 32326624
DOI: 10.3390/pathogens9040289

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