Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA Quantity and Quality Comparisons between Cryopreserved and FFPE Tumors from Matched Pan-Cancer Samples

28 Apr 2024

Abstract excerpt

Personalized cancer care requires molecular characterization of neoplasms. While the research community accepts frozen tissues as the gold standard analyte for molecular assays, the source of tissue for testing in clinical cancer care comes almost universally from formalin-fixed, paraffin-embedded tissue (FFPE). As newer technologies emerge for DNA characterization that requires higher molecular weight DNA, it...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Genetic factors in colorectal cancer
Share to Molecular Biology Techniques and Applications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38785464
DOI: 10.3390/curroncol31050183

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA Quantity and Quality Comparisons between Cryopreserved and FFPE Tumors from Matched Pan-Cancer SamplesPMID 38785464Read ↗

Pre-Analytical Considerations for Successful Next-Generation Sequencing (NGS): Challenges and Opportunities for Formalin-Fixed and Paraffin-Embedded Tumor Tissue (FFPE) SamplesSemantic proximity Read ↗

DNA Yield From Tissue Samples in Surgical Pathology and Minimum Tissue Requirements for Molecular TestingSemantic proximity Read ↗

Comparison of next‑generation sequencing quality metrics and concordance in the detection of cancer‑specific molecular alterations between formalin‑fixed paraffin‑embedded and fresh‑frozen samples in comprehensive genomic profiling with the Illumina® TruSight Oncology 500 assaySemantic proximity Read ↗

Standardization of the preanalytical phase of DNA extraction from fixed tissue for next-generation sequencing analysesSemantic proximity Read ↗

The Japanese Society of Pathology Practical Guidelines on the handling of pathological tissue samples for cancer genomic medicineSemantic proximity Read ↗

Optimizing Workflows and Processing of Cytologic Samples for Comprehensive Analysis by Next-Generation Sequencing: Memorial Sloan Kettering Cancer Center ExperienceSemantic proximity Read ↗

A straightforward assay to evaluate DNA integrity and optimize next-generation sequencing for clinical diagnosis in oncology.Semantic proximity Read ↗

Maximizing the clinical utility and performance of cytology samples for comprehensive genetic profiling – A report on the impact of process optimization through the analysis of 4,871 cytology samples profiled by MSK-IMPACTSemantic proximity Read ↗

Why Formalin-fixed, Paraffin-embedded Biospecimens Must Be Used in Genomic Medicine: An Evidence-based Review and Conclusion.Semantic proximity Read ↗

Use of FFPE-derived DNA in next generation sequencing: DNA extraction methodsSemantic proximity Read ↗

Use of FFPE-Derived DNA in Next Generation Sequencing: DNA extraction methodsSemantic proximity Read ↗

Robustness of Next Generation Sequencing on Older Formalin-Fixed Paraffin-Embedded TissueSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.