DNA Yield From Tissue Samples in Surgical Pathology and Minimum Tissue Requirements for Molecular Testing

Abstract excerpt

CONTEXT: Complex molecular assays are increasingly used to direct therapy and provide diagnostic and prognostic information but can require relatively large amounts of DNA. OBJECTIVES: To provide data to pathologists to help them assess tissue adequacy and provide prospective guidance on the amount of tissue that should be procured. DESIGN: We used slide-based measurements to establish a relationship between...

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