Article
Clonal Hematopoiesis and Bone Marrow Infiltration in Patients With Follicular Helper T-Cell Lymphoma of Angioimmunoblastic Type.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jul 2024
Harland Lennart, Borgmann Vanessa, Otto Franziska, Overkamp Mathis, Bonzheim Irina, Fend Falko, Quintanilla-Martinez Leticia, Nann Dominik
Abstract excerpt
Follicular helper T-cell (TFH) lymphoma harbors recurrent mutations of RHOAG17V, IDH2R172, TET2, and DNMT3A. TET2 and DNMT3A mutations are the most frequently affected genes in clonal hematopoiesis (CH). The aim of our study was to investigate the frequency of CH in bone marrow biopsies (BMB) of TFH/angioimmunoblastic T-cell lymphoma (TFH-AITL) patients and its association with myeloid neoplasms. A total of 29...
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