Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Shared clonal origin of angioimmunoblastic T-cell lymphoma and Burkitt lymphoma arising through divergent evolution from a common precursor.

Journal of hematopathology - 3 Jun 2026

Monika Fnu, Tashkandi Hammad, Yan Mingfei

Abstract excerpt

BACKGROUND: Nodal T follicular helper cell lymphoma, angioimmunoblastic type (AITL), is a common peripheral AQ1T-cell lymphoma characterized by recurrent mutations in TET2, IDH2, DNMT3A, and RHOA, with TET2 and DNMT3A mutations frequently arising in early hematopoietic stem and progenitor cells (HSPCs) as clonal hematopoiesis (CH). In addition to its well-established association with secondary myeloid neoplasms,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Burkitt Lymphoma
Share to Clonal Evolution

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Dioxygenases

Share to DNA-Binding Proteins

Share to RHOA gene

Share to Lymphoma, T-Cell

Share to Mutation

Share to Proto-Oncogene Proteins

Source

Identifiers

PMID: 42234239
DOI: 10.1007/s12308-026-00708-3

Genes

TET2
DNMT3A
RHOA
ID3
IDH2
MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 21 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Shared clonal origin of angioimmunoblastic T-cell lymphoma and Burkitt lymphoma arising through divergent evolution from a common precursor.PMID 42234239Read ↗

Angioimmunoblastic T-cell lymphoma contains multiple clonal T-cell populations derived from a common TET2 mutant progenitor cell.Semantic proximity Read ↗

Clonal hematopoiesis in angioimmunoblastic T-cell lymphoma with divergent evolution to myeloid neoplasms.Semantic proximity Read ↗

Genetic links in angioimmunoblastic T-cell lymphoma (AITL), clonal hematopoiesis and concomitant hematologic malignancies provide insights into the cell of origin, etiology and biomarker discovery for AITLSemantic proximity Read ↗

Parallel evolution of two distinct lymphoid proliferations in clonal haematopoiesis.Semantic proximity Read ↗

Clonal Hematopoiesis and Bone Marrow Infiltration in Patients With Follicular Helper T-Cell Lymphoma of Angioimmunoblastic Type.Semantic proximity Read ↗

Recent Progress in the Understanding of Angioimmunoblastic T-cell Lymphoma.Semantic proximity Read ↗

Mutation analysis links angioimmunoblastic T-cell lymphoma to clonal hematopoiesis and smoking.Semantic proximity Read ↗

The curious origins of angioimmunoblastic T-cell lymphoma.Semantic proximity Read ↗

Advances in the pathogenesis and therapeutic strategies of angioimmunoblastic T-cell lymphoma.Semantic proximity Read ↗

Integrative Genomic and Transcriptomic Analysis Reveals Targetable Vulnerabilities in Angioimmunoblastic T-Cell Lymphoma.Semantic proximity Read ↗

Follicular helper T-cell lymphomas: disease spectrum, relationship with clonal hematopoiesis, and mimics. A report of the 2022 EA4HP/SH lymphoma workshopSemantic proximity Read ↗

Clonal haematopoiesis: A common progenitor for cytotoxic peripheral T-cell lymphoma and angioimmunoblastic T-cell lymphoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.