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Article

Angioimmunoblastic T cell lymphoma: novel molecular insights by mutation profiling.

Oncotarget - 14 Mar 2017

Wang Ming, Zhang Shaowei, Chuang Shih-Sung, Ashton-Key Margaret, Ochoa Eguzkine, Bolli Niccolo, Vassiliou George, Gao Zifen, Du Ming-Qing

Abstract excerpt

Angioimmunoblastic T cell lymphoma (AITL) originates from follicular helper T-cells and is characterised by a polymorphic infiltrate with the neoplastic T-cells forming small clusters around the follicle and high endothelial venules. Despite the recent advances in its phenotypic characterisation, the genetics and molecular mechanisms underlying AITL are not fully understood. In the present study, we performed...

Read the complete abstract on PubMed

Topics

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Share to Adaptor Proteins, Vesicular Transport
Share to Dioxygenases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methyltransferase 3A

Share to Lymphoma, T-Cell

Share to Phospholipase C gamma

Share to Receptors, Tumor Necrosis Factor

Share to rhoA GTP-Binding Protein

Share to T-Lymphocytes, Helper-Inducer

Source

Open in PubMed Open full text

Identifiers

PMID: 28148900
DOI: 10.18632/oncotarget.14846
PMCID: PMC5392284

Genes

PLCG1
RHOA
TET2
TNFRSF21
CCND3
IDH2
SAMSN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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