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Lipase-mediated detoxification of host-derived antimicrobial fatty acids by Staphylococcus aureus

15 May 2024

Abstract excerpt

Long-chain fatty acids with antimicrobial properties are abundant on the skin and mucosal surfaces, where they are essential to restrict the proliferation of opportunistic pathogens such as Staphylococcus aureus. These antimicrobial fatty acids (AFAs) elicit bacterial adaptation strategies, which have yet to be fully elucidated. Characterizing the pervasive mechanisms used by S. aureus to resist AFAs could open...

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PMID: 38750133
DOI: 10.1038/s42003-024-06278-3

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