Article

Investigating the survival response of Staphylococcus aureus to the antimicrobial lipid sphingosine

2018-01-01

Abstract excerpt

The human skin surface is covered with a lipid film that forms the interface between the viable epidermal layers and outer environment, and influences the colonisation of bacteria. Hydrolysis of the epidermal lipid ceramide via ceramidase yields sphingosine, an antimicrobial lipid that is able to kill staphylococci rapidly. Studies of patients with atopic dermatitis have indicated a correlation between levels of s...

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Literature Corpus work: db860f58-1156-5fc2-970a-caa3ad874ad1
DOI: 10.17638/03020133

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