Article
Exploring the Causal Relationship Between Inflammatory Cytokines and Joint Pain: A Mendelian Randomization Study.
Pain research & management - 1 Jan 2026
Yan Zehui, Xi Yujia, Mu Changjiang, Di Jingkai, Guo Zijian, Chen Shuai, Xiang Chuan
Abstract excerpt
Background: Joint pain is a major cause of chronic disability worldwide, with complex mechanisms and limited treatment options. Inflammatory cytokines have been implicated in the pathogenesis of joint pain; however, their causal roles remain unclear. This study employed Mendelian randomization (MR) to explore the causal relationships between 41 inflammatory cytokines and the risk of joint pain. Methods: We...
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