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The effect of inflammatory cytokines on the risk of hypertrophic scar: a mendelian randomization study.

Archives of dermatological research - 21 Aug 2024

Qi Seven, Ma Ashia, Lin Hai, Peng Liangyuan, Deng Eminlam

Abstract excerpt

Hypertrophic scar (HS) results from burns or trauma, causing aesthetic and functional issues. However, observational studies have linked inflammatory cytokines to HS, but the causal pathways involved are unclear. We aimed to determine how circulating inflammatory cytokines contribute to HS formation. Two-sample Mendelian randomization (MR) was used to identify genetic variants associated with hypertrophic scar in...

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Cytokines
Genome-Wide Association Study
Glial Cell Line-Derived Neurotrophic Factor
Leukemia Inhibitory Factor
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Osteoprotegerin

Polymorphism, Single Nucleotide

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PMID: 39167160
DOI: 10.1007/s00403-024-03303-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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