Article
[Effect of the host's body genotype and phenotype on the manifestation of the pathogenic properties of the influenza virus].
Voprosy virusologii - 1 Jan 2000
Semenkov V F, Ageeva O N, Lavrov V F, Korotkov A A, Khodakova L P
Abstract excerpt
The sensitivity of mice of CBA (H-2k haplotype), C57BL/6 (H-2b haplotype) strains and their hybrids M1 and F2 to the pathogenic influenza A/PR8/34 (H0N1) and nonpathogenic A/Krasnodar/101/59 (H2N2) virus strains was studied. The lethality, virus replication in the lungs, and the thymic index were determined. An increase in the resistance to the pathogenic influenza virus was found in male C57BL/6 and male F1 (CBA...
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