Article
[Effect of the host's body genotype and phenotype on the manifestation of the pathogenic properties of the influenza virus].
Voprosy virusologii - 1 Jan 2000
Semenkov V F, Ageeva O N, Lavrov V F, Korotkov A A, Khodakova L P
Abstract excerpt
The sensitivity of mice of CBA (H-2k haplotype), C57BL/6 (H-2b haplotype) strains and their hybrids M1 and F2 to the pathogenic influenza A/PR8/34 (H0N1) and nonpathogenic A/Krasnodar/101/59 (H2N2) virus strains was studied. The lethality, virus replication in the lungs, and the thymic index were...
Topics
- Animals
- Genotype
- Haploidy
- Immunity, Cellular
- Influenza A virus
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Inbred CBA
- Organ Size
- Orthomyxoviridae Infections
- Phenotype
