Article
[Comparative analysis of the biophysical characteristics of influenza A virus variants with differing pathogenicity for mice].
Voprosy virusologii - 1 Jan 2000
Ivanova V T, Zakstel'skaia L Ia, Podcherniaeva R Ia, Blinova V K, Sokolov B P
Abstract excerpt
Variants of influenza A virus: A/PR8/34 Pm-, nonpathogenic for mice and A/PR8/34 Pm+, pathogenic for mice, obtained after 5 passages in mice, were studied. Both variants showed close similarities in the antigenic specificity, high reproductive activity at optimal temperature and reduced activity at low and high temperatures, similar plaque-producing activity in chick fibroblast cell cultures. Differences in their...
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