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Article

[Comparative analysis of the biophysical characteristics of influenza A virus variants with differing pathogenicity for mice].

Voprosy virusologii - 1 Jan 2000

Ivanova V T, Zakstel'skaia L Ia, Podcherniaeva R Ia, Blinova V K, Sokolov B P

Abstract excerpt

Variants of influenza A virus: A/PR8/34 Pm-, nonpathogenic for mice and A/PR8/34 Pm+, pathogenic for mice, obtained after 5 passages in mice, were studied. Both variants showed close similarities in the antigenic specificity, high reproductive activity at optimal temperature and reduced activity at low and high temperatures, similar plaque-producing activity in chick fibroblast cell cultures. Differences in their...

Topics

Animals
Antigens, Viral
Biophysical Phenomena
Biophysics
Chick Embryo
Epitopes
Genetic Variation
Hemagglutinins, Viral
Influenza A virus
Mice
Oligopeptides

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Peptides

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Identifiers

PMID: 6181613

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-6181613-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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