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Article

[Method for the cross protection of mice in studying the antigenic variability of the influenza virus].

Voprosy virusologii - 1 Jan 2000

Briantseva E A, Fridman E A, Peradze T V

Abstract excerpt

A modification of the method of cross protection of mice was developed for the study of influenza virus antigenic drift. This modification does not require a pre-adaptation of the virus to mouse lungs. The experiments of cross protection of immune animals carried out by the modified method demonstrated antigenic variability of the influenza A virus strains (H3N2) isolated in 1968-1983. Immunologically significant...

Topics

Animals
Antigens, Viral
Chick Embryo
Cross Reactions
Genetic Variation
Immunity
Immunization
Influenza A virus
Influenza Vaccines
Mice
Orthomyxoviridae Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Vaccines, Attenuated

Source

Identifiers

PMID: 3992999

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-3992999-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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