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Article

Heterogeneity and molecular landscape of melanoma: implications for targeted therapy.

Molecular biomedicine - 10 May 2024

Beigi Yasaman Zohrab, Lanjanian Hossein, Fayazi Reyhane, Salimi Mahdieh, Hoseyni Behnaz Haji Molla, Noroozizadeh Mohammad Hafez, Masoudi-Nejad Ali

Abstract excerpt

Uveal cancer (UM) offers a complex molecular landscape characterized by substantial heterogeneity, both on the genetic and epigenetic levels. This heterogeneity plays a critical position in shaping the behavior and response to therapy for this uncommon ocular malignancy. Targeted treatments with gene-specific therapeutic molecules may prove useful in overcoming radiation resistance, however, the diverse molecular...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38724687
DOI: 10.1186/s43556-024-00182-2
PMCID: PMC11082128

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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