Genetic Features of Uveal Melanoma.

doi:10.3390/genes15111356

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Article

Genetic Features of Uveal Melanoma.

Genes - 22 Oct 2024

Sorrentino Francesco Saverio, Culiersi Carola, Florido Antonio, De Nadai Katia, Adamo Ginevra Giovanna, Nasini Francesco, Vivarelli Chiara, Mura Marco, Parmeggiani Francesco

Abstract excerpt

BACKGROUND/OBJECTIVES: Although it comprises only 5% of all melanomas, uveal melanoma (UM) is the most commonly observed primary intraocular cancer. METHODS: Poor patient survival persists in spite of innovative systemic therapies. In fact, approximately fifty percent of UM patients develop metastases from micro-metastases that remain undetected at the exact time of diagnosis. RESULTS: The molecular understanding...

Topics

Uveal Neoplasms
Humans
Melanoma
Mutation
Biomarkers, Tumor
Uveal Melanoma

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Identifiers

PMID: 39596556
DOI: 10.3390/genes15111356
PMCID: PMC11593461

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