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Advances in immunotherapy for uveal melanoma: enhancing efficacy and overcoming resistance

30 Jun 2025

Abstract excerpt

Uveal melanoma (UM) is the most common primary intraocular malignancy in adults, presenting a significant clinical challenge due to its high metastatic potential and limited response to conventional systemic therapies. While immunotherapy has transformed the treatment landscape for numerous cancers, its effectiveness in UM has been substantially limited, primarily due to the tumor’s distinct immune-evasive...

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PMID: 40661151
DOI: 10.3389/fcell.2025.1619150

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