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Recent Advances in Molecular and Genetic Research on Uveal Melanoma.

Cells - 12 Jun 2024

Fuentes-Rodriguez Aurélie, Mitchell Andrew, Guérin Sylvain L, Landreville Solange

Abstract excerpt

Uveal melanoma (UM), a distinct subtype of melanoma, presents unique challenges in its clinical management due to its complex molecular landscape and tendency for liver metastasis. This review highlights recent advancements in understanding the molecular pathogenesis, genetic alterations, and immune microenvironment of UM, with a focus on pivotal genes, such as GNAQ/11, BAP1, and CYSLTR2, and delves into the...

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Identifiers

PMID: 38920653
DOI: 10.3390/cells13121023
PMCID: PMC11201764

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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