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Genetic and Epigenetic Features of Uveal Melanoma—An Overview and Clinical Implications

15 Aug 2023

Abstract excerpt

Uveal melanoma (UM) is rare, but it is the most common primary intraocular malignancy among adults. This review represents the molecular, genetic, and immunobiological mechanisms involved in UM carcinogenesis and progression, as well as data about the association of chromosomal changes, genetic mutations, selective proteins, and biochemical biomarkers with the clinical implications of UM. Genetic analysis has the...

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Share to Cutaneous Melanoma Detection and Management
Share to Ocular Oncology and Treatments
Share to Retinal Development and Disorders

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PMID: 37628989
DOI: 10.3390/ijms241612807

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