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Article

Circulating Tumor DNA in Conjunctival Melanoma: Landscape and Surveillance Value.

American journal of ophthalmology - 1 Feb 2025

Tian Hao, Shi Hanhan, Chen Jie, Zhu Tianyu, Huang Ziyue, Zong Chunyan, Jia Shichong, Ruan Jing, Ge Shengfang, Yuan Haihua, Zhang Yanjie, Jiang Bin, Liu Rong, Jia Renbing, Fan Xianqun, Xu Shiqiong

Abstract excerpt

PURPOSE: To evaluate the surveillance value of circulating tumor DNA (ctDNA) for detecting distant metastasis and indicating systemic therapeutic efficacy in conjunctival melanoma (CoM). DESIGN: Retrospective, observational case series. METHODS: From July 2021 to June 2023, 30 CoM patients in our center underwent plasma ctDNA assessment, out of which 12 individuals presented with distant metastases. We employed a...

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Source

Identifiers

PMID: 39424026
DOI: 10.1016/j.ajo.2024.10.012

Genes

BRAF
CTNNB1
KRAS
NF1
NRAS
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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