Proteomic landscaping of high‐grade serous ovarian carcinoma identifies stearoyl‐CoA desaturase 5 as a potential predictive biomarker for poly(ADP‐ribose) polymerase inhibitor response

Abstract excerpt

Dear Editor, High-grade serous ovarian carcinoma (HGSOC) has shown high recurrence and mortality rates despite treatment comprising cytoreductive surgery and chemotherapy.1 However, the recent introduction of poly(ADP-ribose) polymerase inhibitors (PARPi) in the management of HGSOC significantly improved the prognosis.2 As more HGSOC patients receive PARPi treatment, accurately predicting the treatment response...

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