Article

Gene networks and expression quantitative trait loci associated with platinum-based chemotherapy response in high-grade serous ovarian cancer

2019-08-20

Abstract excerpt

<h4>Background</h4> A major impediment in the treatment of ovarian cancer is the relapse of platinum-resistant tumors, which occurs in approximately 25% of patients. A better understanding of the biological mechanisms underlying platinum-based response will improve treatment efficacy through genetic testing and novel therapies. <h4>Methods</h4> Using data from high-grade serous ovarian carcinoma (HGSOC) patients...

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Literature Corpus work: 51fc439f-47bb-567f-a817-03783678dc8d
DOI: 10.1101/740696

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