Article

MicroRNA-Regulated Ubiquitination and Lipid Metabolism Networks are Associated with Chemotherapy Response in Ovarian Cancer

2021-08-04

Abstract excerpt

High-grade serous ovarian cancer (HGSOC) is a highly lethal gynecologic cancer, in part due to resistance to platinum-based chemotherapy reported among 20% of patients. This study aims to characterize the biological mechanisms underlying chemotherapy resistance, which remain poorly understood.Analysis of mRNA/microRNA sequencing data from HGSOC patients of The Cancer Genome Atlas identified 196 differentially expr...

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Literature Corpus work: f95e5bd3-2cf0-5d2e-a5a2-358242e75184
DOI: 10.21203/rs.3.rs-452935/v2

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