Article
Transcription factor shapes chromosomal conformation and regulates gene expression in bacterial adaptation.
Nucleic acids research - 10 Jun 2024
Chen Mao, Wu Bo, Huang Yuhuan, Wang Weiting, Zheng Yudi, Shabbir Samina, Liu Panting, Dai Yonghua, Xia Mengli, Hu Guoquan, He Mingxiong
Abstract excerpt
Genomic mutations allow bacteria to adapt rapidly to adverse stress environments. The three-dimensional conformation of the genome may also play an important role in transcriptional regulation and environmental adaptation. Here, using chromosome conformation capture, we investigate the high-order architecture of the Zymomonas mobilis chromosome in response to genomic mutation and ambient stimuli (acetic acid and...
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