Article
The chromosomal organization of horizontal gene transfer in bacteria.
Nature communications - 10 Oct 2017
Oliveira Pedro H, Touchon Marie, Cury Jean, Rocha Eduardo P C
Abstract excerpt
Bacterial adaptation is accelerated by the acquisition of novel traits through horizontal gene transfer, but the integration of these genes affects genome organization. We found that transferred genes are concentrated in only ~1% of the chromosomal regions (hotspots) in 80 bacterial species. This concentration increases with genome size and with the rate of transfer. Hotspots diversify by rapid gene turnover;...
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