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Article

Germline NGS targeted analysis in adult patients with sporadic adrenocortical carcinoma.

European journal of cancer (Oxford, England : 1990) - 1 Jul 2024

Scatolini Maria, Grisanti Salvatore, Tomaiuolo Pasquale, Grosso Enrico, Basile Vittoria, Cosentini Deborah, Puglisi Soraya, Laganà Marta, Perotti Paola, Saba Laura, Rossini Elisa, Palermo Flavia, Sigala Sandra, Volante Marco, Berruti Alfredo, Terzolo Massimo

Abstract excerpt

BACKGROUND: Adrenocortical carcinoma (ACC) is a rare cancer that arises sporadically or due to hereditary syndromes. Data on germline variants (GVs) in sporadic ACC are limited. Our aim was to characterize GVs of genes potentially related to adrenal diseases in 150 adult patients with sporadic ACC. METHODS: This was a retrospective analysis of stage I-IV ACC patients with sporadic ACC from two reference centers...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38714106
DOI: 10.1016/j.ejca.2024.114088

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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