Article
Adrenocortical tumorigenesis: Lessons from genetics.
Best practice & research. Clinical endocrinology & metabolism - 1 May 2020
Kamilaris Crystal D C, Hannah-Shmouni Fady, Stratakis Constantine A
Abstract excerpt
Advances in genomics over the past two decades have allowed for elucidation of the genetic alterations leading to the development of adrenocortical tumors and/or hyperplasias. These molecular changes were initially discovered through the study of rare familial tumor syndromes such as McCune-Albright Syndrome, Carney complex, Li-Fraumeni syndrome, and Beckwith-Wiedemann syndrome, with the identification of...
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