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Article

The relaxed requirements of the integron cleavage site allow predictable changes in integron target specificity.

Nucleic acids research - 1 Jan 2010

Frumerie Clara, Ducos-Galand Magaly, Gopaul Deshmukh N, Mazel Didier

Abstract excerpt

Integrons are able to incorporate exogenous genes embedded in mobile cassettes, by a site-specific recombination mechanism. Gene cassettes are collected at the attI site, via an integrase mediated recombination between the cassette recombination site, attC, and the attI site. Interestingly, only three nucleotides are conserved between attC and attI. Here, we have determined the requirements of these in...

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Identifiers

PMID: 19914932
DOI: 10.1093/nar/gkp990
PMCID: PMC2811028

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Source receipt: pubmed, retrieved 7 Sept 2026.

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