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Whole-Blood RNA Profiles Associated with Pulmonary Arterial Hypertension and Clinical Outcome

30 Apr 2020

Abstract excerpt

Abstract Rationale Idiopathic and heritable pulmonary arterial hypertension (PAH) are rare but comprise a genetically heterogeneous patient group. RNA sequencing linked to the underlying genetic architecture can be used to better understand the underlying pathology by identifying key signaling pathways and stratify patients more robustly according to clinical risk. Objectives To use a three-stage design of RNA...

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PMID: 32352834
DOI: 10.1164/rccm.202003-0510oc

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