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Article

Molecular mechanisms behind the generation of pro-oncogenic HIV-1 matrix protein p17 variants.

The Journal of general virology - 1 Apr 2024

Zani Alberto, Messali Serena, Bugatti Antonella, Uggeri Matteo, Rondina Alessandro, Sclavi Leonardo, Caccuri Francesca, Caruso Arnaldo

Abstract excerpt

HIV-1 matrix protein p17 variants (vp17s), characterized by amino acid insertions at the COOH-terminal region of the viral protein, have been recently identified and studied for their biological activity. Different from their wild-type counterpart (refp17), vp17s display a potent B cell growth and clonogenic activity. Recent data have highlighted the higher prevalence of vp17s in people living with HIV-1 (PLWH)...

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Share to Cell Line, Tumor
Share to gag Gene Products, Human Immunodeficiency Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Variation

Share to HIV Antigens

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Share to Recombination, Genetic

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Source

Identifiers

PMID: 38687324
DOI: 10.1099/jgv.0.001982

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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