Article
HIV-1 mutants expressing B cell clonogenic matrix protein p17 variants are increasing their prevalence worldwide.
Proceedings of the National Academy of Sciences of the United States of America - 5 Jul 2022
Caccuri Francesca, Messali Serena, Zani Alberto, Campisi Giovanni, Giovanetti Marta, Zanussi Stefania, Vaccher Emanuela, Fabris Silvia, Bugatti Antonella, Focà Emanuele, Castelli Francesco, Ciccozzi Massimo, Dolcetti Riccardo, Gallo Robert C, Caruso Arnaldo
Abstract excerpt
AIDS-defining cancers declined after combined antiretroviral therapy (cART) introduction, but lymphomas are still elevated in HIV type 1 (HIV-1)-infected patients. In particular, non-Hodgkin's lymphomas (NHLs) represent the majority of all AIDS-defining cancers and are the most frequent cause of death in these patients. We have recently demonstrated that amino acid (aa) insertions at the HIV-1 matrix protein p17...
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