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Article

Genetic susceptibility to chronic diseases leads to heart failure among Europeans: the influence of leukocyte telomere length.

Human molecular genetics - 6 Jul 2024

Wong Jason Y Y, Blechter Batel, Liu Zhonghua, Shi Jianxin, Roger Véronique L

Abstract excerpt

BACKGROUND: Genetic susceptibility to various chronic diseases has been shown to influence heart failure (HF) risk. However, the underlying biological pathways, particularly the role of leukocyte telomere length (LTL), are largely unknown. We investigated the impact of genetic susceptibility to chronic diseases and various traits on HF risk, and whether LTL mediates or modifies the pathways. METHODS: We conducted...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38676403
DOI: 10.1093/hmg/ddae063
PMCID: PMC11227624

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