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Evidence that Telomere Length is Causal for Idiopathic Pulmonary Fibrosis but not Chronic Obstructive Pulmonary Disease: A Mendelian Randomisation Study

2020-02-07

Abstract excerpt

<h4>Summary</h4> <h4>Background</h4> Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease accounting for 1% of UK deaths. In the familial form of pulmonary fibrosis, causal genes have been identified in ∼30% of cases, and a majority relate to telomere maintenance. Prematurely shortened leukocyte telomere length has also been associated with IPF, as well as chronic obstructive pulmonary disease (COPD), a dis...

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Literature Corpus work
ac81e14e-63db-5af6-a26b-eac6ab252798
DOI
10.1101/2020.02.05.20019653
Open publication

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Evidence that Telomere Length is Causal for Idiopathic Pulmonary Fibrosis but not Chronic Obstructive Pulmonary Disease: A Mendelian Randomisation StudyDOI 10.1101/2020.02.05.20019653
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