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Breaking down causes, consequences, and mediating effects of telomere length variation on human health

17 May 2024

Abstract excerpt

BACKGROUND: Telomeres form repeated DNA sequences at the ends of chromosomes, which shorten with each cell division. Yet, factors modulating telomere attrition and the health consequences thereof are not fully understood. To address this, we leveraged data from 326,363 unrelated UK Biobank participants of European ancestry. RESULTS: Using linear regression and bidirectional univariable and multivariable Mendelian...

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Birth, Development, and Health
Epigenetics and DNA Methylation
Telomeres, Telomerase, and Senescence

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38760657
DOI: 10.1186/s13059-024-03269-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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